Even if we tried to observe protein folding processes by experiment, they cannot be seen at the atomic resolution. So, molecular simulation on a computer is a powerful method to observe the processes in which the protein is being folded. Force field is a set of parameters that define structures and energetics of a protein during molecular simulation. Accuracy of the molecular simulation depends on accuracy of the force field. Moreover, the force field can influence the protein structure that is determined by X-ray and NMR methodologies.
In our laboratory, the SAAP force field that allows highly accurate and high-speed simulation is being developed.
>Jump to "SAAP Project"
