Recent Activity

"Development of the high-speed simulation technology by using the SAAP Force Field"
was adopted for Research and Study Program of Tokai University Education System
General Research Organization. (June 30, 2005)


SAAP

In the proteome analysis and the research of genome-based medicine, it is required to determine the protein structure and the interactions clearly at the atomic resolution and to predict and simulate the dynamic movements rapidly and accurately. However, there is a limit in achieving the high accuracy and speed by improvement or modification of prior technologies. In this project, by using the single amino acid potential force field (SAAP) originally developed in Iwaoka laboratory, it is planed to develop a new simulation technology (integrated software) that can simulate a protein structure far more accurately and at a far higher speed than previous conventional methods. It is expected that a usual personal computer comes to be able to execute the forecast simulation of a protein structure easily. Thus, a common, technological base of the life science research can be changed completely if this technology is succeeded.

The participation members of the research endeavor involve Toshiya Minezaki (associate professor of School of Science, Tokai University) and Dr. Shigeru Ishikawa (associate professor of School of Science, Tokai University). It aims at the completion of the alpha-version program by the end of fiscal year 2005.

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